Status:
Ready to upload
Record number:
1822
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
20 known reports in Asia; this is first known reported case in a Western country.
Time to detection:
Until lab results from surgical fluid sample were identified; stool positive within 5-6 days.
Alerting signals, symptoms, evidence of occurrence:
During transplant noted bile duct drained fluid with black specks and sent for path review. Stool samples from recipient and donor postoperative day 5-6 were positive using merthiolate iodine formaldehyde concentration (MIFC) technique for trematode eggs.
Demonstration of imputability or root cause:
Fluid from bile duct drainage of living donor organ sent from the surgery demonstrated Opisthorchis felineus infestation. Stool samples from both donor and recipient post-op demonstrated trematode eggs. Recipient was six months old in liver failure, had lived in Germany her entire life and food exposures highly unlikely at her age. On retrospective extensive donor history, donor had history of eating dried fish in Kazakhstan during yearly visits to relatives.
Imputability grade:
3 Definite/Certain/Proven
Groups audience:
Suggest new keywords:
Colonorchis, living donor liver transplant
Reference attachment:
Suggest references:
Liver fluke-infested graft used for living-donor liver transplantation: case report and review of the literature. Capobianco et al. Transpl Infect Dis. 17(6):880-5, 2015 Dec.
Expert comments for publication:
Liver grafts infested with liver flukes do not pose absolute contraindication to liver donation from deceased or living donors, provided that a correct diagnosis and treatment are performed in a timely fashion.