Ready to upload
Adverse Occurrence type:
Time to detection:
Occurs during GCSF injections (although has been described to occur several days later in at least one case).
Alerting signals, symptoms, evidence of occurrence:
Demonstration of imputability or root cause:
Renal biopsy. Definite imputability (if biopsy-proven).
1) Lee JB, Billen A, et al. Exacerbation of IgA nephropathy following G-CSF administration for PBSC collection: suggestions for better donor screeningBone Marrow Transplant. 2016 Feb;51(2):286-7. 2) Funakoshi, Y, Nazneen A, et al. Possible involvement of G-CSF in IgA nephropathy developing in an allogeneic peripheral blood SCT donor. Bone Marrow Transplant, 2010, Volume 45, Issue 9, p.1477 - 1478
The WMDA annual report 2015 should be added to record 501(Bronwen)
Expert comments for publication:
Uncommon although documented causal link of haematuria provoked by GCSF injection due to underlying IgA nephropathy.