Hemolysis secondary to IVIG

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Record number: 
Adverse Occurrence type: 
MPHO Type: 
Estimated frequency: 
Infrequent, not rare
Time to detection: 
Immediate to first few days post infusion
Alerting signals, symptoms, evidence of occurrence: 
Hemolysis, rapid drop in hct/hgb
Demonstration of imputability or root cause: 
Positive DAT with eluate showing same specificity as identified in IVIG sample
Imputability grade: 
3 Definite/Certain/Proven
Groups audience: 
Suggest new keywords: 
IVIG, hemolysis
Suggest references: 
I think this is good to include as it indicates both lyophilized and liquid can be involved in AHTR but maybe another paper on hemolytic events and IVIG is needed.