Antibody-mediated hemolysis

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Record number: 
Adverse Occurrence type: 
MPHO Type: 
Estimated frequency: 
Infrequent, not rare
Time to detection: 
Immediate to within a few days of transfusion of IVIg
Alerting signals, symptoms, evidence of occurrence: 
Hemolysis, dropping hct/hgb
Demonstration of imputability or root cause: 
+DAT with eluate having same specificity as found in IVIG product
Imputability grade: 
3 Definite/Certain/Proven
Groups audience: 
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This article can be combined or linked with record 1764. All of them are under the same category of hemolysis following IVIG transfusion
Expert comments for publication: 
Review article on multiple pathophysiological pathways towards hemolysis after IVIG transfusion