Case Report: Mycosis fungoides (2014)

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Record number: 
Adverse Occurrence type: 
MPHO Type: 
Estimated frequency: 
Most recent risk assessment for leukemia, lymphoma and plasmacytoma (Council of Europe, 2022): Leukaemia, lymphoma and plasmacytoma diagnosed during donor procurement: These cancers are classified as an unacceptable risk for organ donation. Leukaemia, lymphoma and plasmacytoma in the donor history: Active (acute or chronic) leukaemia, lymphoma and plasmacytoma are an unacceptable risk for organ donation. Treated acute leukaemia and lymphoma after a definite disease-free interval of 10 years may be considered for organ donation with an assumed high risk for transmission.
Time to detection: 
8 years
Alerting signals, symptoms, evidence of occurrence: 
Erythematous plaque on left axila, with skin biopsy consistent with mycosis fungoides, stage IA.
Demonstration of imputability or root cause: 
Same disease diagnosed in the donor, assumed to be present at the time of donation based on the retrospective review of photographs of the donor at the time of the bone marrow donation, with lesions consistent with mycosis fungoides. Polymerase chain reaction of specimens from both donor and recipient shows identical clonal peaks at the T-cell receptor gamma locus." Donor died from mycosis fungoides. Recipient with disease at the time of report.
Imputability grade: 
3 Definite/Certain/Proven
Groups audience: 
Suggest new keywords: 
hematological malignancy
mycosis fungoides
erythematous plaque
Suggest references: 
"Loh J, Cassarino D, Grody W, Chiu M, Pinter-Brown L. A Case of Mycosis Fungoides Transmitted From Donor to Recipient, and Review of Literature of T-Cell Malignancies After Transplantation. Clinical Lymphoma, Myeloma & Leukemia, 2014; Vol. 14, No. 4, e137-40"
Record n.1584 has been divided into two records based on taxonomy, depending on how the user is searching. They may search for skin tumors or may search for T cell lymphomas. This would fit under both (1. …malignancy/Skin/Skin cancer, other or type not specified and 2. ...Malignancy/Blood and lymphoid/Lymphoma, T cell)