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Adverse Occurrence type:
Time to detection:
Alerting signals, symptoms, evidence of occurrence:
Donor became short of breath immediately after donation, dizzy, with severe shortness of breath within 12 hours. Ventilation/Perfusion (V/Q) scan showed bilateral small peripheral embolisms in the lungs.
Demonstration of imputability or root cause:
Positive V/Q scan.
Suggest new keywords:
Basu M, Georgsen J, Assing K. (2015). Pulmonary embolism after blood donation in a healthy young female. Transfusion Medicine
Expert comments for publication:
The donor was a healthy 18 year old female, previous blood donor. Venipuncture was atraumatic. She had no family or genetic predisposition to thrombophilia. She was a non-smoker. Laboratory workup showed normal levels of antithrombin, cardiolipin antibodies, protein C and S and no specific Factor V Leiden or Factor 2 gene mutations. Her only risk factor was use of third generation combined oral contraceptives.