Lung cancer (Bronchogenic carcinoma) after kidney transplant (1965)

Status:

Ready to upload

Record number:

1539

Adverse Occurrence type:

Lung cancer, squamous cell (bronchogenic)

MPHO Type:

Kidney

Estimated frequency:

Most recent risk assessment for Lung Cancer (Council of Europe, 2022): Any histotype of newly-diagnosed lung cancer is an unacceptable risk for organ donation. Lung cancer in the donor history: Treated lung cancer is considered to be associated with a high transmission risk. Risk may decrease after curative therapy, with recurrence-free time and with increasing probability of cure.

Time to detection:

3.5 months

Alerting signals, symptoms, evidence of occurrence:

The recipient complained of pain in the right flank, extending from the rib cage to the area of the grafted kidney in the right iliac fossa.

Demonstration of imputability or root cause:

The donor had known bronchogenic carcinoma with brain metastases. Later autopsy showed widespread metastases. (Transplant performed 1965). The tumor from the graft biopsy was histopathologically identical to that of the donor based on the biopsy result and concluded to be donor bronchogenic carcinoma.

Imputability grade:

3 Definite/Certain/Proven

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