Status:
Ready to upload
Record number:
1533
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
The prevalence of iron deficiency in donors: new female donors 12.0% males 1.3%, female whole blood (WB)-only donors 26.4% (it increased with donation frequency and decreased with age). The prevalence in male WB-only donors was 6.3% with no evident change with age or donation frequency. The prevalence of iron deficiency in apheresis-only donors (females 6.3%; males 2.2%) did not significantly exceed that of new donors nor did it change with donation frequency.
Time to detection:
24 months
Alerting signals, symptoms, evidence of occurrence:
In order to investigate the effects of donation type and frequncy on the epidemiology of iron deficiency, mean ferritin (ng/mL) and Hb (gr/dL) were considered in donors who made at least 1 until more than 6 WB donations in the previous 24 months.
Demonstration of imputability or root cause:
There is a significant inverse correlation between ferritin concentration and total 24 months equivalent WB loss.
Imputability grade:
3 Definite/Certain/Proven
Groups audience:
References:
Reference attachment:
Suggest references:
Salvin, H.E., Sant-Rayn, P., Marks, D.C. and Speedy, J. (2014). Iron deficiency in blood donors: a national cross-sectional study. Transfusion 54(10): 2434-44.