Status:
Ready to upload
Record number:
1486
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
TRALI rates stated prior to and post- implementation of plateletpheresis and plasma from males or nulligravida or HLA-antibody negative parous females. RBC's: 0.5 per 100,000 units; Plateletpheresis: 2.8 to 1.0 per 100,000; Plasma: 3.6 to 0.4 per 1000,000.
Time to detection:
<6 hours
Alerting signals, symptoms, evidence of occurrence:
Reports to a large regional blood center with rates reported as TRALI cases per product distributed/tranfused.
Demonstration of imputability or root cause:
Criteria not presented
Imputability grade:
1 Possible
Groups audience:
Keywords:
References:
Suggest references:
Shaz BH. Bye-bye TRALI: by understanding and innovation. Blood. 2014;123:3374-6.
Expert comments for publication:
TRALI rates provided in an Editorial addressing TRALI mitigation devices/mediators.