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Adverse Occurrence type:
Time to detection:
Alerting signals, symptoms, evidence of occurrence:
No HTLV-related symptoms. Infection detected through routine follow up screening for blood borne viruses following emergency transfusion of unscreened blood after sustaining severe injuries whilst in combat. Screening is done according to US miltary protocol. Antibody reactivity detected at 19 days and confirmed at 22 days post transfusion.
Demonstration of imputability or root cause:
Recipient showed initial antibody reactivity at day 19 post transfusion, with an indeterminate Western Blot pattern; fully confirmed seroconversion on day 44. Donor found to be seropositive. Molecular markers relatedness of donor and recipient strains demonstrated by sequencing.
Suggest new keywords:
Shilpa Hakre, Mark M. Manak, Clinton K, et al. Transfusion-transmitted human T-lymphotropic virus Type I infection in a United States military emergency whole blood transfusion recipient in Afghanistan, 2010. TRANSFUSION 2013;53:2176-2182.