Human immunodeficiency virus (HIV)

Retrospective analysis started once the donor was discovered to be an intrevenous drug abuser. Donor's frozen blood sample at the time of transplant positive for IgG anti-HIV, IgM negative. Recipient IgG and IgM anti-HIV negative at the time of bone marrow transplant. Seroconversion at 5 months post transplantation, with different pattern of antibody response of donor and recipient obtained from immunoblotting analysis (continued antigenic stimulation due to the presence of HIV infected cells, transient production of IgM anti-HIV).