Anaplasma phagocytophilum

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Record number: 
Adverse Occurrence type: 
MPHO Type: 
Estimated frequency: 
Transfusion-transmitted anaplasmosis frequency varies widely depending on incidence in the donor population, which varies geographically.
Time to detection: 
Alerting signals, symptoms, evidence of occurrence: 
Recipient was gunshot wound victim diagnosed by laboratory testing exclusively, including granulocyte inclusions evident on day 5 after transfusion, PCR positive on day 22 after transfusion. Also with thrombocytopenia and granulocyte toxic granulations. Recipient died of unrelated causes.
Demonstration of imputability or root cause: 
Recipient PCR positive; donor was IgM and IgG positive 70 days after collection. Co-component was transfused but recipient not tested and died of unrelated causes.
Imputability grade: 
2 Probable
Suggest references: 
Townsend, R.L., Moritz, E.D., Fialkow, L.B., Berardi, V. and Stramer, S.L. (2014). Probable transfusion-transmission of Anaplasma phagocytophilum by leukoreduced platelets. Transfusion DOI 10.1111/trf.12675.