Arterial thrombosis

Status:

Ready to upload

Record number:

1289

Adverse Occurrence type:

Cardiovascular

MPHO Type:

Platelets

Estimated frequency:

In HIT, there are 6.90% arterial thromboses those with platelet transfusions versus 3.06% in those without i.e. 3.84% extra thrombosis with platelet transfusions. Thus, for every 26 patients receiving platelet transfusions, we will expect one additional arterial thrombosis. In TTP, there are 1.79% arterial thromboses those with platelet transfusions versus 0.35% in those without. Thus, for every 75 patients receiving platelet transfusions, we will expect one additional arterial thrombosis.

Alerting signals, symptoms, evidence of occurrence:

Data base review.

Demonstration of imputability or root cause:

Primary and secondary diagnosis codes.

Imputability grade:

2 Probable

Groups audience:

Clinical complications

Keywords:

HIT (heparin induced thrombocytopenia)

TTP (thrombotic thrombocytopenic purpura)

References:

Platelet transfusions in platelet consumptive disorders are associated with arterial thrombosis and in-hospital mortality.

Reference attachment:

Arterial thrombosis, Goel, 2015.pdf

Suggest references:

Goel, R., Ness, P,M., Takemoto, C.M., Krishnamurti, L.,King, K.E. and Tobian, A.A. (2015). Platelet transfusions in platelet consumptive disorders are associated with arterial thrombosis and in-hospital mortality. Blood 125(9):1470-1476. DOI: 10.1182/blood-2014-10-605493.