Allergic/hypersensitivity reactions, PAS platelets

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Record number: 
Adverse Occurrence type: 
MPHO Type: 
Estimated frequency: 
0.29% in platelet prepared with additive solutions vs. 0.82% (plasma) per platelet transfusion; per patient the incidence was 0.83% versus 3.13%, respectively.
Alerting signals, symptoms, evidence of occurrence: 
Per National Healthcare Safety Network criteria. Active surveillance for transfusion adverse events was conducted by blinded observers.
Demonstration of imputability or root cause: 
Retrospective review.
Imputability grade: 
2 Probable
Groups audience: 
Suggest references: 
Cohn, C.S., Stubbs, J., Schwartz, J., Francis, R., Goss, C., Cushing, M., Shaz, B., Mair, D., Brantigan, B. and Heaton, A. (2014). A comparison of adverse reaction rates for PAS C versus plasma platelet units. Transfusion54:1927-1934.