Allergic/hypersensitivity reactions, platelets

Ready to upload
Record number: 
Adverse Occurrence type: 
MPHO Type: 
Estimated frequency: 
1.9% (Kaufman). Platelets stored in additive solution versus plasma 0.29% vs. 0.82%, respectively (Cohn).
Time to detection: 
Within 4 hours
Alerting signals, symptoms, evidence of occurrence: 
Common Terminology Criteria for Adverse Event (Kaufman). Biovigilance Component of National Healthcare Safety Network (Cohn)
Demonstration of imputability or root cause: 
Clinical criteria as reviewed by expert panel
Imputability grade: 
2 Probable
Groups audience: 
Suggest references: 
Kaufman, R.M., Assmann, S.F., Triulzi, D.J., Strauss, R.G., Ness, P., Granger, S. and Slichter, S.J. (2015). Transfusion-related adverse events in the Platelet Dose study. Transfusion 55(1):144-153; Cohn, C.S., Stubbs, J., Schwartz, J., Francis, R., Goss, C., Cushing, M., Shaz, B., Mair, D., Brantigan, B. and Heaton, A. (2014). A comparison of adverse reaction rates for PAS C versus plasma platelet units. Transfusion54:1927-1934.