Status:
Ready to upload
Record number:
1274
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
Febrile, non-hemolutic reaction rate for RBC transfusions in an elderly US population: 70.5 per 100,000 inpatient transfusion stays. Odds of reaction occurrence increase with increasing number of units transfused, female vs. male (OR=1.15), and patients with lymphoma (OR=1.22) and leukemia (OR=1.90). Rates increase with 1-year history of blood transfusion and decrease with increasing patient age.
Time to detection:
N/A
Alerting signals, symptoms, evidence of occurrence:
Diagnosis based on ICD-9-CM coding. Specific time interval not stated. Fever, chills, rigors, headache, nausea and/or vomiting.
Demonstration of imputability or root cause:
Retrospective administrative record review subject to over- and under- reporting and misclassifiction.
Imputability grade:
2 Probable
Groups audience:
Keywords:
Reference attachment:
Suggest references:
Menis, M., Forshee, R.A., Anderson, S.A., McKean, S., Gondalia, R., Warnock, R., Johnson, C., Mintz, P.D., Worrall, C.M., Kelman, J.A. and Izurieta, H.S. (2014). Febrile non-haemolytic transfusion reaction occurrence and potential risk factors among the U.S. elderly transfused in the inpatient setting, as recorded in Medicare databases during 2011-2012. Vox Sang DOI: 10.1111/vox.12215