Febrile nonhemolytic transfusion reactions (FNHTR)

Status:

Ready to upload

Record number:

1272

Adverse Occurrence type:

Febrile reaction

MPHO Type:

Red blood cells

Estimated frequency:

Acute transfusion reaction rate= 9.6% of 507 red cell or whole blood units transfused on adult or pediatric patients on medical, surgical, obstetrical, and gynecologic wards who were not bleeding. No patients receiving cancer chemotherapy or with cardiac illnesses were included. All blood was not leukocyte reduced. Study occurred in Uganda, a resource-limited country. Overall rates: FNHTR= 4.9 per 100 units; TACO=0.6 per 100 units; Acute transfusion reactions= 0.4 per 100 units; allergic reactions= 1.4 per 100 units.

Time to detection:

Up to 4 hours after transfusion

Alerting signals, symptoms, evidence of occurrence:

Fever greater than 1°C, 20 mmHg change in systolic or diastolic blood pressure or other vital signs.

Demonstration of imputability or root cause:

Defined criteria and panel review

Imputability grade:

2 Probable

Groups audience:

Clinical complications

Keywords:

FNHTR (febrile non hemolytic transfusion reaction)

RBC (red blood cell)

resource limited country

fever

adult

pediatric

References:

Acute transfusion reactions at a national referral hospital in Uganda: a prospective study.

Suggest new keywords:

febrile reactions in resource-limited country

Reference attachment:

* ATR,FNHTR Waiswa, 2014.pdf

Suggest references:

Waiswa, M.K., Moses, A., Seremba, E., Ddungu,H. and Hume, H.A. (2014). Acute transfusion reactions at a national referral hospital in Uganda: a prospective study. Transfusion 54(11):2804-2810.