Acute Hemolytic Transfusion Reaction (AHTR), anti-A, renal failure

Status:

Ready to upload

Record number:

1270

Adverse Occurrence type:

Acute Hemolytic Reaction

MPHO Type:

Red blood cells

Estimated frequency:

Case report

Time to detection:

2-4 minutes

Alerting signals, symptoms, evidence of occurrence:

A unit of group AB Rh-positive red cells was inadvertently infused at a group O Rh-positive patient. Shock, loss of consciousness.

Demonstration of imputability or root cause:

Shock

Imputability grade:

3 Definite/Certain/Proven

Groups audience:

Clinical complications

Keywords:

AHTR (acute hemolytic transfusion reaction)

RBC (red blood cell)

acute renal failure

LOC (loss of consciousness)

References:

Hemolytic transfusion reaction occurring in a patient with acute renal failure.

Reference attachment:

* AHTR renal failure, Hoffsten, 2015.pdf

Suggest references:

Hoffsten, P.E. and Chaplin, H. Jr. (1969). Hemolytic transfusion reaction occurring in a patient with acute renal failure. Blood 33(2):234-239.

Expert comments for publication:

Listed under anti-A, but given the fact that the implicated unit was group AB into a group O recipient with high strength antibodies, it is likely that antibodies directed against both A and B were implicated.