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Adverse Occurrence type:
Time to detection:
Alerting signals, symptoms, evidence of occurrence:
Following the transfusion, patient had bilirubin and urobilinogen in his urine and a fall in haemoglobin of nearly 2 g dL (-1).
Demonstration of imputability or root cause:
Clinical and serology results.
Suggest new keywords:
Cherian. G., Search, S., Thomas, E., Poole, J., Davies, S.V. and Massey, E. (2007). An acute haemolytic transfusion reaction caused by anti-Wr. Transfus Med 17(4):312-314.
Expert comments for publication:
Anti-Wra of the Diego system, a relatively common antibody to an antigen of very low frequency, has caused severe hemolytic transfusion reactions. It has also been implicated in delayed hemolytic transfusion reactions.