Status:
Ready to upload
Record number:
1261
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
Case Report
Time to detection:
3 days
Alerting signals, symptoms, evidence of occurrence:
Patient with history of documented anti-Ge3 alloantibody who received multiple units of Ge+ red blood cells (RBCs) came in to receive 8 units of Ge+ RBCs with no incident. 4.5 years later the patient received 2 units of Ge+ RBCs and developed clinical and laboratory signs consistent with AHTR.
Demonstration of imputability or root cause:
Serology and no increase in hemoglobin concentration
Imputability grade:
2 Probable
Groups audience:
Keywords:
Suggest new keywords:
anti-Ge3, acute hemolytic transfusion reaction (AHTR),
Reference attachment:
Suggest references:
Baughn, M.R., Whitacre, P., Los, G.S., Pandey, S. and Lane, T.A. (2011). A mild acute hemolytic transfusion reaction in a patient with alloanti-Ge3: a case report and review of the literature. Transfusion 51(9): 1966-1971.
Expert comments for publication:
Mild reaction, said to be first clinically significant report of Anti-Ge.