Peanut allergy

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Record number: 
Adverse Occurrence type: 
MPHO Type: 
Estimated frequency: 
Rare. 7.7% of Canadian blood donors have severe allergies.
Time to detection: 
immediately - 4 days
Alerting signals, symptoms, evidence of occurrence: 
Patient received two apheresis platelet transfusions from A) a donor with peanut allergy and B) subsequent apheresis platelet transfusion from a donor who had ingested peanuts. Immediately, patient developed pruritits and hives at time of transfusion. Four days following the index transfusion, while at home, she developed peri-oral and peri-orbital edema, and epiphora immediately after consuming peanut butter.
Demonstration of imputability or root cause: 
Suspected passive transfer of IgE peanut antibodies following transfusion of platelet concentrate.
Imputability grade: 
2 Probable
Groups audience: 
Suggest references: 
Ponnampalam, A., Growe, G., Loftus, P., Chipperfield, K. and Bigham, M. (2014). Acquired peanut hypersensitivity following platelet transfusion. Transfus Med DOI 10.1111/tme.12148