Record number:
1140
Adverse Occurrence type:
MPHO Type:
Alerting signals, symptoms, evidence of occurrence:
Patient received 2 CBU units. One was RBC replete. A volume of 126 mls of lysed RBC was infused. Transfusion of lysed red cells, nitric oxide scavenging by free Hb, vasospasm/smooth muscle spasm w severe, widespread pain. Gross haemoglobinuria. Able to be managed with aggressive fluid resuscitation with preservation of renal function and without long term sequelae.
Demonstration of imputability or root cause:
Related to infusion
Suggest references:
World Marrow Donor Association.S(P)EAR Committee Annual Report - year 2012