Loss of embryos of 12 couples due to incorrect mix of cryopreservation medium

Record number: 
1121
Adverse Occurrence type: 
MPHO Type: 
Estimated frequency: 
Never reported before, simular case in 2013, less severe
Alerting signals, symptoms, evidence of occurrence: 
Detected when first embryos where thawed.
Demonstration of imputability or root cause: 
All embryos cryopreserved degenerated. The mix of self made cryopreservation medium didn't contain DMSO.
Suggest references: 
TRIP annual report 2013 Biovigilance