Record number:
1103
Adverse Occurrence type:
MPHO Type:
Estimated frequency:
Never reported before
Time to detection:
1 day
Alerting signals, symptoms, evidence of occurrence:
Acute renal insufficiency (anuria, edema, high creatinine) 24 hours after transplantation of autologous bone marrow in a 14 months old patient. Dialysis necessary and IC treatment. No hemolysis.
Demonstration of imputability or root cause:
DMSO concentration normal. Medication pre-transplant: Cyclosporine, Thiotepa, Busulfan, Fludarabine. Renal insufficiency due to medication possible
References:
Suggest references:
TRIP annual report 2012 Biovigilance