Acute renal insufficiency

Record number: 
Adverse Occurrence type: 
MPHO Type: 
Estimated frequency: 
Never reported before
Time to detection: 
1 day
Alerting signals, symptoms, evidence of occurrence: 
Acute renal insufficiency (anuria, edema, high creatinine) 24 hours after transplantation of autologous bone marrow in a 14 months old patient. Dialysis necessary and IC treatment. No hemolysis.
Demonstration of imputability or root cause: 
DMSO concentration normal. Medication pre-transplant: Cyclosporine, Thiotepa, Busulfan, Fludarabine. Renal insufficiency due to medication possible
Suggest references: 
TRIP annual report 2012 Biovigilance