G6PD deficiency

Record number:

1101

Adverse Occurrence type:

MPHO Type:

Estimated frequency:

uncommon

Time to detection:

Years

Alerting signals, symptoms, evidence of occurrence:

Acute hemolysis (jaundice, hemoglobinuria, fever, back pain, anemia)

Demonstration of imputability or root cause:

Unbalanced X-inactivation pattern in patient and donor

Keywords:

acute hemolysis

G6PD (glucose-6-phosphate dehydrogenase)

G6PD deficiency

X-linked recessive

References:

First episode of acute hemolysis due to G6PD deficiency in a middle-aged woman and transmission of the enzymatic defect through bone marrow transplant.

Suggest references:

Orlandi, E, et al, 2004. First episode of acute hemolysis due to G6PD deficiency in a middle-aged woman and transmission of the enzymatic defect through bone marrow transplant. Haematologica 89:ECR04.