TACO (Transfusion-associated Circulatory Overload)

Record number:

1083

Adverse Occurrence type:

Transfusion-Associated Circulatory Overload (TACO)

MPHO Type:

Red blood cells

Estimated frequency:

Various rates cited: 1 per 4075 RBC transfusions, prevalence rate at one hospital 1 per 68 RBC transfusions.

Time to detection:

<6 hours

Alerting signals, symptoms, evidence of occurrence:

Acute respiratory distress, elevated BNP, elevated CVP, evidence of left heart failure, evidence of positive fluid balance, CXR showing pulmonary edema.

Demonstration of imputability or root cause:

Variable

Keywords:

TACO (transfusion associated circulatory overload)

RBC (red blood cell)

heart failure

acute respiratory distress

pulmonary edema

chest x-ray

References:

How we view and approach transfusion-associated circulatory overload: pathogenesis, diagnosis, management, mitigation, and prevention.

Suggest references:

Andrzejewski C, Casey MA, Popovsky MA. How we view and approach transfusion-associated cardiac overload: pathogenesis, diagnosis, management, mitigation, and prevention. Transfusion 2013;53:3037-47