TAD (Transfusion-associated dyspnea)

Record number: 
1074
Adverse Occurrence type: 
MPHO Type: 
Estimated frequency: 
Total TACO cases 34.8 per 1,000,000 components transfused. Mortality 4.4 and major morbidity 12.3 per 1,000,000 components transfused.
Time to detection: 
<6 hours
Alerting signals, symptoms, evidence of occurrence: 
Acute respiratory distress, acute worsening of pulmonary edema, evidence of positive fluid balance, evidence of volume intolerance
Demonstration of imputability or root cause: 
Expert review including cited alerting criteria and ISBT definition
Suggest references: 
Bolton-Maggs, PHB (Ed), D Poles, A Watt and D Thomas on behalf of the Serious Hazards of Transfusion (SHOT) Steering Group, UK (2014). The 2013 Annual SHOT Report (2014), p 166-73. ISBN 978-0-9558648-6-5