Pseudomonas aeruginosa

Record number: 
1026
Adverse Occurrence type: 
MPHO Type: 
Time to detection: 
4 days
Alerting signals, symptoms, evidence of occurrence: 
Recipient 1: fever, abdominal pain, and drainage from the surgical incision. Blood cultures obtained when transplant team was notified of positive donor culture results, were positive for Pseudomonas aeruginosa on day +4. The P. aeruginosa isolated from blood was found to be MDR, sensitive only to polymyxin B and amikacin, and the patient was started on polymixin B. Recipient 2 died from pseudomonal infection.
Demonstration of imputability or root cause: 
Recipient’s isolate from blood and the donor isolate from the lungs were found to be indistinguishable by pulse-field gel electrophoresis, confirming the diagnosis of donor-derived infection due to MDR P. aeruginosa.
Imputability grade: 
3 Definite/Certain/Proven
Suggest references: 
Simkins J, Muggia V. Favorable outcome in a renal transplant recipient with donor-derived infection due to multidrug-resistant Pseudomonas aeruginosa. Transpl Infect Dis 2012;14:292-5.