Record number:
1022
Adverse Occurrence type:
MPHO Type:
Time to detection:
19 days
Alerting signals, symptoms, evidence of occurrence:
Three-day history of fever (38°C)
Demonstration of imputability or root cause:
Positive blood cultures after 48 hours for a gram negative rod, identified as P. oralis according to biochemical testing, metabolic end-products analysis, and cell-wall fatty acid profiling by use of gas liquid chromatography. A repeated aortic valve replacement was undertaken but no bacterial growth was revealed in the excised graft (gram staining of the aortic homograft revealed gram-negative rods, but after long incubation in appropriate media and anaerobic atmosphere cultures of the specimen were negative). No portal of entry of P. oralis could be detected retrospectively.
Imputability grade:
1 Possible
Keywords:
Reference attachment:
Suggest references:
Quaglio, G., et al., Prevotella oralis homograft-valve endocarditis complicated by aortic-root abscess, intracardiac fistula, and complete heart block. Clin Infect Dis, 1999. 28(3): p. 685-6.