Adverse Occurrence type:
Alerting signals, symptoms, evidence of occurrence:
Febrile Non Hemolytic Transfusion Reaction (FNHTR) characterized by increase in temperature above 38°C, or chills and rigor in the absence of fever, with no evidence of hemolysis. Tachycardia, elevated blood pressure.
Demonstration of imputability or root cause:
The blood culture results and timing suggested that these patients likely had catheter-related bloodstream infections caused by transfusion through a CVC with subclinical microbial colonization.
Ricci, K.S., Martinez, F., Lichtiger, B. and Han, X.Y. (2014). Septic transfusion reactions during blood transfusion via indwelling central venous catheters. Transfusion 54(10): 2412-18.