Record number: 
Adverse Occurrence type: 
MPHO Type: 
Time to detection: 
1 week
Alerting signals, symptoms, evidence of occurrence: 
30 yr old male penetrating keratoplasty (PK) for keratoconus. After one week developed eye pain, ciliary injection, graft edema, keratitic precipitates. Regrafted after 1 month. Excised button: Acanthamoeba cysts in stroma. Recurred again, had 3rd graft after 3 months. Donor asymptomatic.
Demonstration of imputability or root cause: 
Definite. Two corneas from one donor transmitted infection after PK. Both infections shown to be from common source by genomic analysis (from same donor).
Imputability grade: 
3 Definite/Certain/Proven
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