%0 Journal Article %J American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons// Am J Transplant %D 2015 %T Donor-derived Strongyloides stercoralis infection in solid organ transplant recipients in the United States, 2009-2013. %A Abanyie, F A %A Gray, E B %A Delli Carpini, K W %A Yanofsky, A %A McAuliffe, I %A Rana, M %A Chin-Hong, P V %A Barone, C N %A Davis, J L %A Montgomery, S P %A Huprikar, S %K *Donor Selection/mt [Methods] %K *Strongyloides stercoralis %K *Strongyloidiasis/co [Complications] %K *Transplantation %K Adult %K Aged %K Animals %K Centers for Disease Control and Prevention (U.S.) %K Female %K Humans %K Immunocompromised Host %K Kidney Transplantation/ae [Adverse Effects] %K Latin America %K Liver Transplantation/ae [Adverse Effects] %K Male %K Middle Aged %K Postoperative Complications %K Strongyloidiasis/ep [Epidemiology] %K Tissue Donors %K Transplant Recipients %K United States %X Infection with Strongyloides stercoralis is typically asymptomatic in immunocompetent hosts, despite chronic infection. In contrast, immunocompromised hosts such as solid organ transplant recipients are at risk for hyperinfection syndrome and/or disseminated disease, frequently resulting in fatal outcomes. Infection in these recipients may result from reactivation of latent infection or infection through transmission from an infected donor. We describe the Centers for Disease Control and Prevention's experience with seven clusters of donor-derived infection from 2009 to 2013. Six of the seven (86%) donors were born in Latin America; donor screening was not performed prior to organ transplantation in any of these investigations. Eleven of the 20 (55%) organ recipients were symptomatic, two of whom died from complications of strongyloidiasis. We also describe the New York Organ Donor Network (NYODN) experience with targeted donor screening from 2010 to 2013. Of the 233 consented potential donors tested, 10 tested positive for Strongyloides antibody; and 18 organs were transplanted. The majority (86%) of the donors were born in Central or South America. Fourteen recipients received prophylaxis after transplantation; no recipients developed strongyloidiasis. The NYODN experience provides evidence that when targeted donor screening is performed prior to transplantation, donor-derived infection can be averted in recipients. © Copyright 2015 The American Society of Transplantation and the American Society of Transplant Surgeons. %B American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons// Am J Transplant %C United States %V 15 %P 1369 - 75 %8 2015// %@ 1600-6143 %G eng %N 5 %< http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=medl&NEWS=N&AN=25703251