TY - JOUR T1 - Human T lymphotropic virus type-1-associated myelopathy manifesting shortly after living-donor renal transplantation. JF - Internal medicine (Tokyo, Japan)// Intern Med Y1 - 2015 A1 - Nagamine, Yuito A1 - Hayashi, Takeshi A1 - Kato, Yuji A1 - Horiuchi, Yohsuke A1 - Tanahashi, Norio KW - *Antiviral Agents/tu [Therapeutic Use] KW - *Human T-lymphotropic virus 1/py [Pathogenicity] KW - *Interferon-alpha/tu [Therapeutic Use] KW - *Kidney Transplantation/ae [Adverse Effects] KW - *Living Donors KW - *Paraparesis, Tropical Spastic/dt [Drug Therapy] KW - *Paraparesis, Tropical Spastic/vi [Virology] KW - Adult KW - Female KW - Humans KW - Paraparesis, Tropical Spastic/di [Diagnosis] KW - Treatment Outcome AB - A 38-year-old woman experienced numbness in both lower extremities and spastic paralysis a few months after undergoing living-donor renal transplantation. The patient was negative for human T lymphotropic virus type-1 (HTLV-1) antibodies prior to the procedure; however, she was diagnosed with HTLV-1-associated myelopathy (HAM) based on positive serum and cerebrospinal fluid antibody titers after the surgery. Because the donor was also positive for HTLV-1 antibodies, the infection likely originated from the transplanted kidney. Clinical and imaging improvements were noted following the administration of interferon-alpha. HAM has been reported to occur after living-donor renal transplantation; however, there are no previous reports of onset within such a short period. M1 - bd6, 9204241 CY - Japan VL - 54 SN - 1349-7235 CP - 1 L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=medl&NEWS=N&AN=25742898 ID - 4505 ER -