TY - JOUR T1 - Delayed hemolytic transfusion reaction caused by a primary immune response. JF - Transfusion//Transfusion Y1 - 1982 A1 - Patten, E A1 - Reddi, C R A1 - Riglin, H A1 - Edwards, J KW - *Anemia, Hemolytic/et [Etiology] KW - *Blood Transfusion/ae [Adverse Effects] KW - Adult KW - Anemia, Hemolytic/im [Immunology] KW - Antibody Affinity KW - Antibody Formation KW - Female KW - Humans KW - Infant, Newborn KW - Lewis Blood-Group System/im [Immunology] KW - Male KW - Rh-Hr Blood-Group System/im [Immunology] KW - Time Factors AB - Delayed hemolytic transfusion reactions usually occur as a result of a secondary immune response with maximal hemolysis occurring seven days posttransfusion. We report a delayed hemolytic transfusion reaction in which hemoglobinuria, anemia, and reticulocytosis developed four weeks after transfusion. The incriminated antibody, anti-C, was first detected eight weeks posttransfusion using enzyme-treated red blood cells. We conclude, that in all likelihood, this hemolytic transfusion reaction was due to a primary immune response, this case illustrates the importance of sequential testing in cases of suspected transfusion reactions. M1 - wdn, 0417360 CY - UNITED STATES VL - 22 SN - 0041-1132 CP - 3 L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=med2&NEWS=N&AN=6806951 ID - 4395 ER -