TY - JOUR T1 - Review of the risk of HIV infection through corneal transplantation in the United States JF - J Am Optom Assoc Y1 - 1994 A1 - Caron,M. J. A1 - Wilson,R. KW - Acquired Immunodeficiency Syndrome / transmission KW - Cornea / microbiology KW - Corneal Transplantation / *adverse effects KW - Eye Infections, Viral / *transmission KW - HIV / growth & development KW - HIV Infections / *transmission KW - Humans KW - Keratoplasty, Penetrating / adverse effects KW - Risk Factors KW - Tissue Donors KW - United States AB - BACKGROUND: Human immunodeficiency virus (HIV), the pathogen that causes acquired immunodeficiency syndrome (AIDS), has been isolated in the corneal epithelium of some HIV-positive patients. This observation raises concern about the risk of HIV transmission through corneal transplantation surgery (penetrating keratoplasty). METHODS: A comprehensive review of the literature of the ocular transmission of HIV, screening of donor corneas, and the potential of HIV transmission through penetrating keratoplasty was conducted and analyzed to review and interpret the relative risk of HIV infection through corneal transplantation. RESULTS: No cases of HIV transmission were found as a result of routine eye care or ophthalmic surgical procedures, including HIV-serp-negative recipients who inadvertently received HIV-seropositive corneas. CONCLUSIONS: While ocular transmission of HIV appears to be remote, there are still relative risks of HIV transmission due to ophthalmic surgical procedures. Careful screening of donors for HIV infection affords an important increase in the margin of safety for corneal transplantation recipients. VL - 65 ER - internal-pdf://Caron - Review of risk of HIV-4217572609/Caron - Review of risk of HIV.pdf CP - 3 N1 - Caron, M J Wilson, R Review United states Journal of the American Optometric Association J Am Optom Assoc. 1994 Mar;65(3):173-8. ID - 297 ER -