TY - JOUR T1 - HBV transmission from an occult carrier with five mutations in the major hydrophilic region of HBsAg to an immunosuppressed plasma recipient. JF - Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology// J Clin Virol Y1 - 2013 A1 - Coppola, Nicola A1 - Loquercio, Giovanna A1 - Tonziello, Gilda A1 - Azzaro, Rosa A1 - Pisaturo, Mariantonietta A1 - Di Costanzo, Gaetano A1 - Starace, Mario A1 - Pasquale, Giuseppe A1 - Cacciapuoti, Carmela A1 - Petruzziello, Arnolfo KW - *Blood Component Transfusion/ae [Adverse Effects] KW - *Carrier State/vi [Virology] KW - *Hepatitis B Surface Antigens/ge [Genetics] KW - *Hepatitis B/di [Diagnosis] KW - *Hepatitis B/tm [Transmission] KW - *Immunocompromised Host KW - *Mutation, Missense KW - Aged KW - Carrier State/di [Diagnosis] KW - DNA, Viral/bl [Blood] KW - Hepatitis B Surface Antigens/bl [Blood] KW - Hepatitis B/vi [Virology] KW - Humans KW - Male KW - Viral Load AB - We describe the case of transmission of an HBsAg-negative hepatitis B infection to an immunosuppressed patient by plasma donation from an HBsAg-negative subject, but with very low serum HBV DNA (about 50 IU/ml) and five mutations in the major hydrophilic region of HBsAg.Copyright © 2013. Published by Elsevier B.V. M1 - cx0, 9815671 CY - Netherlands VL - 58 SN - 1873-5967 CP - 1 L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=medl&NEWS=N&AN=23856167 ID - 4537 ER -