01907nas a2200217   4500008004100000020001400041024001700055245006600072210006300138260029900201520099500500100001501495700001801510700001801528700001801546700002101564700001901585700001801604700002201622856004501644       2015                        eng d  a0041-1132  awdn, 041736000aReal-time symptomatic case of transfusion-transmitted dengue.0 aRealtime symptomatic case of transfusiontransmitted dengue  a(C) 2015 John Wiley & Sons, Ltdb(1)Fundacao Pro-Sangue, Hemocentro de Sao Paulo, University of Sao Paulo, Sao Paulo, Brazil; (2)Virology Lab, Instituto de Medicina Tropical da Universidade de Sao Paulo, University of Sao Paulo, Sao Paulo, Brazil; and (3)Department of Infectious and Parac20153 aBACKGROUND: Dengue virus transmission by blood transfusion is a rarely reported event., CASE REPORT: During a dengue outbreak in Sao Paulo city, a regular plateletpheresis donor informed the blood bank of being diagnosed a few days after donation. The recipient was hospitalized and displayed symptoms and laboratory evidence of dengue after transfusion., RESULTS: The donor was immunoglobulin (Ig)G, IgM, and polymerase chain reaction nonreactive on the index sample, seroconverting 20 days later. The platelet units were transfused into two patients. One of them developed fever 3 days after transfusion, with high viral load. His pretransfusion sample was negative for IgG, IgM, and dengue RNA, while the second recipient did not show any symptoms nor laboratory evidence of dengue infection., CONCLUSIONS: This case brings additional evidence that dengue is indeed transmissible by blood transfusion and clinical manifestations, although rare, do occur., (C) 2015 John Wiley & Sons, Ltd1 aLevi, Jose1 aNishiya, Anna1 aFelix, Alvina1 aSalles, Nanci1 aSampaio, Luciana1 aHangai, Fatima1 aSabino, Ester1 aMendrone, Alfredo  uhttps://notifylibrary.org/reference/4296