02294nas a2200229   4500008004500000022001400045245008800059210006900147260002100216300000700237490000600244520154800250653001101798653001101809653000701820653005301827653004701880653001401927100001601941700001701957856009001974       2003                        Engldsh    a1355-478600aReview of clinical course and treatment of ovarian hyperstimulation syndrome (OHSS)0 aReview of clinical course and treatment of ovarian hyperstimulat  aEnglandcJan-Feb  a770 v93 aThe ovarian hyperstimulation syndrome (OHSS) is a rare iatrogenic complication of ovarian stimulation occurring during the luteal phase or during early pregnancy. This complication is unusual as it is not the consequence of a treatment which is vital or mandatory for the patient's health. Nevertheless, it can be accompanied by severe morbidity and may even be fatal. Data pertaining to the clinical course and consequences of OHSS in women and its treatment were searched using Medline, Current Contents and PubMed. To date, only a few studies have collected a large number of cases of OHSS. The clinical course of OHSS may involve, according to its severity and the occurrence of pregnancy, electrolytic imbalance, neurohormonal and haemodynamic changes, pulmonary manifestations, liver dysfunction, hypoglobulinaemia, febrile morbidity, thromboembolic phenomena, neurological manifestations and adnexal torsion. Treatment of the acute phase relies only on an empirical and symptomatic approach. The general approach will be adapted to the levels of severity. Specific approaches such as paracentesis, pleural puncture, surgical approach of OHSS and specific medication during OHSS were evaluated sporadically. More adequate treatment methods would require a better understanding of the underlying pathophysiological mechanisms, to promote an aetiological therapeutic approach. Properly conducted studies, including large numbers of patients are required in order to determine the best method of prevention and management. [References: 221]10aFemale10aHumans10aIM10aOvarian Hyperstimulation Syndrome / th [Therapy]10aOvulation Induction / ae [Adverse Effects]10aPregnancy1 aDelvigne, A1 aRozenberg, S  uhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=12638783