01400nas a2200181   4500008003900000245013700039210006900176300001200245490000700257520082300264100001501087700001601102700001101118700001201129700001601141700001701157856004401174       2002                          d00aMarginal keratitis associated with administration of filgrastim and sargramostim in a healthy peripheral blood progenitor cell donor0 aMarginal keratitis associated with administration of filgrastim   a621 - 20 v213 aPURPOSE: To describe a 61-year-old healthy peripheral blood progenitor cell (PBPC) donor who developed marginal keratitis and mild uveitis on the third day after receiving daily recombinant human granulocyte colony-stimulating factor (rhG-CSF; filgrastim) and recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF; sargramostim) to mobilize PBPCs for allogeneic transplantation. METHODS: Interventional case report. RESULTS: The keratitis was treated with topical administration of 1% prednisolone acetate solution and resolved within 24 hours. The topical steroid dose was tapered and ultimately discontinued without recurrence of keratitis. CONCLUSION: Healthy PBPC donors receiving rhG-CSF or rhGM-CSF should be monitored for ocular complications, particularly marginal keratitis and uveitis.1 aEsmaeli, B1 aAhmadi, M A1 aKim, S1 aOnan, H1 aKorbling, M1 aAnderlini, P  uhttps://notifylibrary.org/reference/488