01867nas a2200217   4500008003900000245014900039210006900188260000800257300001100265490000700276520120400283100001601487700001701503700001401520700001501534700001201549700001301561700001301574700001701587856004501604       2019                          d00aRenal cell carcinoma suspected at time of organ donation 2008-2016: A report of the OPTN ad hoc Disease Transmission Advisory Committee Registry0 aRenal cell carcinoma suspected at time of organ donation 2008201  cJul  ae135970 v333 aAll 179 reports to the OPTN of potential renal cell carcinoma (RCC) transmission from 1/1/2008 through 12/31/2016 were reviewed. Cases were divided into those with donor tumor known or suspected at time of transplant (N = 147 donors), and those in which tumor was initially found after transplant (N = 32). We sought to understand the risk of transplanting either the affected kidney, the contralateral kidney or non-renal organs from donors with a suspected/confirmed unilateral RCC. In the case of RCC found prior to transplant, transplantation of 21 kidneys following excision of tumor, 47 contralateral kidneys and 198 non-renal organs was performed. No cases of RCC transmission were documented in this population. An additional six cases of live donor kidney transplantation involving resection of RCC were reported, also without transmission. Six of 9 other recipients in whom the diagnosis of RCC became available after implantation underwent allograft nephrectomy and 3 received tumor resection. No recurrent RCC was documented. Given the low rate of transmission and available treatment options, consideration should be given to judicious use of organs from donors with small solitary RCC.1 aPavlakis, M1 aMichaels, MG1 aTlusty, S1 aTurgeon, N1 aVece, G1 aWolfe, C1 aWood, RP1 aNalesnik, MA  uhttps://notifylibrary.org/reference/4888