@article {4193,
	title = {A mild acute hemolytic transfusion reaction in a patient with alloanti-Ge3: a case report and review of the literature.},
	journal = {Transfusion//Transfusion},
	volume = {51},
	year = {2011},
	month = {2011},
	pages = {1966 - 71},
	publisher = {Baughn,Mariah R. Department of Pathology, University of California, San Diego, La Jolla, CA 92093-0960, USA.},
	address = {United States},
	abstract = {BACKGROUND: The clinical significance of the Gerbich antibodies has been described as variable and there are no well-documented reports of hemolytic transfusion reactions (HTRs)., CASE REPORT: We present the case of a woman with a long history of documented anti-Ge3 alloantibody who received multiple units of Ge+ red blood cells (RBCs) uneventfully. During the first admission to our hospital she was transfused 8 units of Ge+ RBCs and had a negative monocyte monolayer assay (MMA) before receiving the units. Within 2 weeks of the transfusions, the anti-Ge3 became significantly stronger by indirect antiglobulin test, and the MMA increased from 2.2 to 79.5\% reactivity. She returned 4.5 years later with an emergent need for blood and was transfused with 2 units of Ge+ RBCs after premedication with steroids and intravenous immunoglobulin., RESULTS: The first unit was transfused without incident; however, she developed clinical and laboratory signs consistent with an acute HTR with the second unit., CONCLUSION: After a comprehensive review of the literature, we believe this to be the first well-documented case of acute HTR due to anti-Gerbich alloantibodies.Copyright {\textcopyright} 2011 American Association of Blood Banks.},
	keywords = {*Blood Transfusion/ae [Adverse Effects], *Glycophorin/im [Immunology], *Hemolysis/im [Immunology], *Isoantibodies/im [Immunology], Adult, Erythrocyte Transfusion/ae [Adverse Effects], Female, Humans},
	isbn = {1537-2995},
	author = {Baughn, Mariah R and Whitacre, Patricia and Lo, Grace S and Pandey, Suchitra and Lane, Thomas A}
}
