@article {4158,
	title = {Transfusion-transmitted anaplasmosis from leukoreduced red blood cells.},
	journal = {//Transfusion},
	volume = {53},
	year = {2013},
	month = {2013},
	pages = {181 - 186},
	publisher = {(1) From the Blood Bank and Transfusion Medicine, the Division of Infectious Disease, The Miriam Hospital, and the Rhode Island Blood Center, Providence, Rhode Island; and Imugen, Inc., Norwood, Massachusetts.},
	address = {Copyright (C) 2013 Blackwell Publishing Ltd.},
	abstract = {BACKGROUND: Human granulocytic anaplasmosis (HGA) is a tick-borne rickettsial infectious disease. To date four cases of transfusion-transmitted anaplasmosis (TTA) have been described in the literature, and only one from leukoreduced red blood cells (RBCs)., CASE REPORT: A 64-year-old patient with acute gastrointestinal blood loss was admitted to the hospital and received 5 units of prestorage leukoreduced RBCs. He was stabilized and discharged. He developed headache, fever, and chills 2 days after discharge and was readmitted. On Day 5 of his second admission polymorphonuclear leukocytes containing morulae consistent with HGA were reported in the peripheral smear., RESULTS: Samples from the recipient tested positive by polymerase chain reaction (PCR) for Anaplasma phagocytophilum, the causative agent of HGA and a segment from one of the five donors tested positive by both serology and PCR., CONCLUSION: Leukoreduction theoretically reduces the risk of TTA but does not interdict all infections. TTA requires consideration in recipients of RBC transfusion with unexplained fever., Copyright (C) 2013 Blackwell Publishing Ltd.},
	isbn = {0041-1132},
	author = {Alhumaidan, Hiba and Westley, Benjamin and Esteva, Carlos and Berardi, Victor and Young, Carolyn and Sweeney, Joseph}
}
