@article {4117,
	title = {Donor anti-Jk(a) causing hemolysis in a liver transplant recipient.},
	journal = {Transfusion//Transfusion},
	volume = {42},
	year = {2002},
	month = {2002},
	pages = {363 - 7},
	publisher = {Hareuveni,Mara. Sourasky Medical Center, Tel Aviv, Israel.},
	address = {United States},
	abstract = {BACKGROUND: Hemolytic transfusion reactions have been observed in recipients of ABO- and/or D-mismatched marrow, peripheral blood, and solid organs. Passenger lymphocyte syndrome occurs when immunocompetent donor lymphocytes transferred during transplantation produce alloantibodies against host antigens., CASE REPORT: The first case of a delayed, anti-Jk(a)-mediated hemolytic reaction in a liver transplant recipient, caused by passenger donor lymphocytes, is reported here. A 43-year-old man underwent liver transplantation. Six weeks later, the patient underwent a second liver transplant. On Day 10 of the second transplant, clinical hemolysis ensued; anti-Jk(a) was detected. The patient{\textquoteright}s DAT became positive, and anti-Jk(a) was eluted from his RBCs. On Day 35 of the patient{\textquoteright}s second transplant, 3 weeks after the last blood transfusion, the patients{\textquoteright} DAT was still weakly positive with anti-Jk(a) in the eluate. Six months later, serum antibody screening was negative, but the DAT was still weakly positive. The patient{\textquoteright}s RBCs tested Jk(a+), whereas the second donor{\textquoteright}s RBCs were Jk(a-)., CONCLUSION: This is the first documentation of clinically significant hemolysis caused by anti-Jk(a), produced by passenger lymphocytes transferred from the donor{\textquoteright}s liver to the transplant recipient.},
	keywords = {*Hemolysis/im [Immunology], *Kidd Blood-Group System/im [Immunology], *Liver Transplantation, *Lymphocytes/im [Immunology], *Tissue Donors, ABO Blood-Group System/im [Immunology], Adult, Anemia, Hemolytic/im [Immunology], Blood Group Incompatibility/im [Immunology], Blood Grouping and Crossmatching, Blood Transfusion, Erythrocytes/im [Immunology], Humans, Immunosuppressive Agents/tu [Therapeutic Use], Isoantibodies/bl [Blood], Male},
	isbn = {0041-1132},
	author = {Hareuveni, Mara and Merchav, Hadar and Austerlitz, Neomi and Rahimi-Levene, Naomi and Ben-Tal, Ofira and Rahimi-Leveen, Neomi}
}
