@article {1800,
	title = {Quantitative Epstein-Barr virus shedding and its correlation with the risk of post-transplant lymphoproliferative disorder.},
	volume = {26},
	year = {2012},
	note = {Status: In-Process; Publishing Model: Journal available in: Print-Electronic Citation processed from: Internet; NLM Journal Code: bb5, 8710240; Grant Number: 2P01 DK13083 (United States NIDDK NIH HHS)},
	month = {Sep-Oct},
	pages = {1},
	address = {Denmark},
	abstract = {We postulated that quantitative monitoring of Epstein-Barr virus (EBV) shedding after transplantation could distinguish EBV-associated illnesses and predict clinical outcome. EBV DNA was measured in solid organ (SOT) and hematopoietic cell transplants (HCT) using our own real-time TaqMan EBV PCR. The proportion of patients who had EBV DNAemia post-transplant was significantly lower in HCT vs. SOT (p =1 whole blood sample vs. 13 (2\%) of 755 patients who had at least three EBV-negative blood samples and were never positive. PTLD risk in viremic patients increased with the peak quantity of EBV DNAemia (p 10(5) (p < 0.001). EBV PCR was predictive in 29 (78\%) of 37 patients tested within three wk prior to tissue diagnosis of PTLD, and thus, we conclude that EBV PCR with careful attention paid to changes in EBV DNAemia could lead to earlier diagnosis and treatment of PTLD. 2012 John Wiley \& Sons A/S.},
	keywords = {IM},
	issn = {0902-0063},
	doi = {http://dx.doi.org/10.1111/j.1399-0012.2012.01608.x},
	author = {Holman,C. J. and Karger,A. B. and Mullan,B. D. and Brundage,R. C. and Balfour,H. H.,Jr}
}
