@article {1778,
	title = {Microbial contamination of hematopoietic progenitor cell products: clinical outcome},
	volume = {40},
	year = {2007},
	note = {JID: 8702459; 2007/06/18 [aheadofprint]; ppublish},
	month = {Aug},
	pages = {5},
	address = {England},
	abstract = {We reviewed the results of routine microbiological assays of 3078 infused hematopoietic progenitor cell (HPC) products for autologous and allogeneic transplantation between January 2001 and December 2005. Thirty-seven (1.2\%) contaminated products were found. All patients receiving contaminated infusions received empirical antibiotic prophylaxis according to the assay result. None of these patients developed a positive blood culture with the same agent, developed infections that could be attributable to the contaminated product or experienced any clinical sequelae. Coagulase-negative Staphylococcus was found in 32 (86.5\%) products. Admission lengths and time to engraftment were within the expected time frame for autologous and allogeneic transplants. Microbial contamination of HPC products occurs at a low frequency; prophylactic use of antibiotics based on the microbiological assay appears to be effective in preventing clinical complications.},
	keywords = {Antibiotic Prophylaxis / methods, Bacteremia / prevention \& control, Blood Component Removal / methods, Cross Infection / microbiology / prevention \& control, Hematopoietic Stem Cell Transplantation / adverse effects, Hematopoietic Stem Cells / microbiology, Humans, Medical Audit, Retrospective Studies, Texas, Transplantation, Autologous, Transplantation, Homologous},
	issn = {0268-3369; 0268-3369},
	doi = {10.1038/sj.bmt.1705731},
	author = {Patah,P. A. and Parmar,S. and McMannis,J. and Sadeghi,T. and Karandish,S. and Rondon,G. and Tarrand,J. and Champlin,R. and de Lima,M. and Shpall,E. J.}
}
