@article {1656,
	title = {ABO mismatch increases transplant-related morbidity and mortality in patients given nonmyeloablative allogeneic HPC transplantation},
	journal = {Transfusion},
	volume = {43},
	year = {2003},
	note = {Worel, Nina Kalhs, Peter Keil, Felix Prinz, Erika Moser, Karin Schulenburg, Axel Mitterbauer, Margit Mannhalter, Christine Mayr, Wolfgang R Schwarzinger, Ilse Hocker, Paul Lechner, Klaus Greinix, Hildegard T United States Transfusion Transfusion. 2003 Aug;43(8):1153-61.},
	month = {Aug},
	pages = {1153 - 61},
	edition = {37821},
	abstract = {BACKGROUND: ABO mismatch has not been thought to affect the outcome of patients undergoing myeloablative conditioning and allogeneic HPC transplantation. Data on transplant-related complications after ABO-mismatched transplantation after nonmyeloablative conditioning are limited. STUDY DESIGN AND METHODS: Therefore, 40 patients were analyzed after nonmyeloablative conditioning with regard to ABO compatibility. Eleven received a minor and bidirectional and 8 a major ABO-mismatched graft. RESULTS: Four patients had evidence of hemolysis during engraftment, being lethal in one, and three developed pure RBC aplasia. Six patients in the ABO-mismatched group developed thrombotic microangiopathy, and three of them died. ABO-identical and ABO-mismatched patients had a similar incidence of GVHD. Viral infections occurred in both groups in equal shares. Patients with an ABO-mismatch had to be rehospitalized until Day 100 for a median of 19 days versus 0 days in the identical group (p < 0.05). Overall survival was 60 and 57 percent in the ABO-identical and ABO-mismatch groups, respectively. The probability of transplant-related mortality was 0 versus 28 percent in the identical group compared to patients with an ABO mismatch (p < 0.05). The probability of relapse or progression was 76 versus 25 percent in the ABO-identical group compared to the ABO-mismatched group, respectively. CONCLUSION: Significantly more patients with ABO mismatch showed transplant-associated complications and died as a result of transplant-related causes.},
	keywords = {*ABO Blood-Group System, Adult, Aged, Blood Group Incompatibility / *complications, Central Nervous System Diseases / etiology, Disease Progression, Female, Graft vs Host Disease / etiology, Hematologic Diseases / etiology, Hematopoietic Stem Cell Transplantation / *adverse effects / *mortality, Hospitalization, Humans, Immune System Diseases / etiology, Infection / etiology, Male, Middle Aged, Recurrence, Survival Analysis, Transplantation, Homologous},
	issn = {0041-1132 (Print) 0041-1132 (Linking)},
	doi = {465 [pii]},
	author = {Worel,N. and Kalhs,P. and Keil,F. and Prinz,E. and Moser,K. and Schulenburg,A. and Mitterbauer,M. and Mannhalter,C. and Mayr,W. R. and Schwarzinger,I. and Hocker,P. and Lechner,K. and Greinix,H. T.}
}
