@article {1433,
	title = {Organ-cultured corneal grafts from septic donors: a retrospective study},
	journal = {Eye (Lond)},
	volume = {16},
	year = {2002},
	note = {Spelsberg, H Reinhard, T Sengler, U Daeubener, W Sundmacher, R England Eye (London, England) Eye (Lond). 2002 Sep;16(5):622-7.},
	month = {Sep},
	pages = {622 - 7},
	edition = {37492},
	abstract = {PURPOSE: To evaluate the quality of corneal grafts from donors, who have died from septic multi-organ failure and who are called septic donors in the following. METHODS: One hundred and eighty-two corneal grafts from septic donors were stored in organ culture for 10-14 days. Graft evaluation was performed according to the criteria of the European Eye Bank Association. Only donor corneas with cell density values above 2000 cells/mm(2) were transplanted. Ninety-one patients who received these transplanted corneas were examined retrospectively with special emphasis on endophthalmitis, graft failure and incidence of immune reactions. RESULTS: Ninety-one of 182 donor corneas (50\%) from septic donors were discarded mainly due to endothelial damage (61; 67\%). Only seven (8\%) were discarded due to medium contamination. In contrast, 452 of 1261 donor corneas (36\%) from non-septic donors during the same period were discarded, again mainly due to endothelial damage (264; 58\%). In this group, 48 donor corneas (11\%) were discarded due to medium contamination. No patient who had received a graft from a septic donor has experienced endophthalmitis. The rate of immune reactions and graft failure was in the same range when compared to a larger group who received grafts from non-septic donors. CONCLUSION: Our data reveal no contraindication against the use of corneal grafts derived from septic donors, critical graft assessment in organ culture provided.},
	keywords = {*Postoperative Complications, *Tissue Donors, Adolescent, Adult, Aged, Aged, 80 and over, Corneal Transplantation / *contraindications / immunology, Culture Media, Drug Contamination, Endophthalmitis / *etiology, Follow-Up Studies, Graft Rejection, Humans, Middle Aged, Organ Culture Techniques, Retrospective Studies, Sepsis / *transmission},
	issn = {0950-222X (Print) 0950-222X (Linking)},
	doi = {10.1038/sj.eye.6700145},
	url = {internal-pdf://spelsberg - septic donors-2744261888/spelsberg - septic donors.pdf},
	author = {Spelsberg,H. and Reinhard,T. and Sengler,U. and Daeubener,W. and Sundmacher,R.}
}
