@article {1368,
	title = {Methicillin-resistant Staphylococcus aureus infection in liver transplantation: a matched controlled study},
	journal = {Transplant Proc},
	volume = {37},
	year = {2005},
	note = {0041-1345 (Print) Journal Article},
	month = {Mar},
	pages = {1243 - 4},
	abstract = {The purpose of this study was to evaluate the clinical impact of methicillin-resistant Staphylococcus aureus (MRSA) infections on transplant recipients. METHODS: Liver and kidney recipients with MRSA infections were retrospectively identified and compared to an age, gender, UNOS status, organ transplanted, and transplant date matched (2:1) non-MRSA-infected recipient control group. All MRSA infections were initially treated with vancomycin, and four (33\%) liver recipients were converted to linezolid therapy after failing to improve with vancomycin. RESULTS: The overall MRSA infection incidence was 1.4\% (24/1770) with MRSA more common in liver (3.75\%; 12/320) than kidney transplants (0.8\%; 12/1450) (P < .001). The most common sites of MRSA infection were blood (42\%), lung (38\%), and abdomen (29\%). The MRSA group had a greater percentage of prior antibiotic usage (79\% vs 40\%; P < .0015). The MRSA group experienced more posttransplant complications (52\% vs 19\%; P < .011)), and exhibited a trend toward greater length of stay in the intensive care unit (7.8 vs 4.6 days; P = .09), but not overall length of stay. Survival was similar in MRSA and non-MRSA groups (75\% vs 88\%; P = .17). No significant differences in mortality were noted between liver and kidney recipients infected with MRSA (P = .6). CONCLUSION: MRSA infection is associated with a higher incidence of posttransplant complications and antibiotic usage in both liver and kidney recipients compared to patients with MRSA infection.},
	keywords = {*Liver Transplantation, Acetamides / therapeutic use, Female, Humans, Incidence, Intensive Care Units, Length of Stay, Male, Methicillin Resistance, Oxazolidinones / therapeutic use, Postoperative Complications / epidemiology / *microbiology, Retrospective Studies, Staphylococcal Infections / drug therapy / *epidemiology / mortality, Survival Analysis, Vancomycin / therapeutic use},
	author = {Schneider,C. R. and Buell,J. F. and Gearhart,M. and Thomas,M. and Hanaway,M. J. and Rudich,S. M. and Woodle,E. S.}
}
