@article {1343, title = {Transferral of extrathoracic donor neoplasm by the cardiac allograft}, journal = {J Heart Lung Transplant}, volume = {16}, year = {1997}, note = {Sack, F U Lange, R Mehmanesh, H Amman, K Schnabel, P Zimmermann, R Dengler, T Otto, H F Hagl, S Case Reports United states The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation J Heart Lung Transplant. 1997 Mar;16(3):298-301.}, month = {Mar}, pages = {298 - 301}, edition = {35490}, abstract = {The transference of neoplasm from the donor to the recipient is a rare but recognized complication of organ transplantation. It has been reported after kidney transplantation from cadaver donors. We report a case in which an extrathoracic tumor was transmitted by the donor heart. The donor heart was harvested from a 46-year-old local donor and immediately transplanted to a 62-year-old female recipient. While implantation was performed, a hypernephroma was detected in the multiorgan donor. The ongoing heart transplantation could not be stopped. Four weeks after operation, the patient was discharged from the hospital. During the first year after transplantation, the clinical course was uneventful. One year after operation, the patient was admitted to the hospital with symptoms of weakness and fever. A right facial hemiparesis occurred, and a soft tumor was palpable subcutaneously in the right supraorbital region. Histologic examination revealed a malignant tumor with characteristics identical to the donor hypernephroma. In spite of chemotherapy and radiation therapy, dramatic tumor progression occurred with multiorgan metastases, which led to the death of the patient 2 months after admission.}, keywords = {*Neoplasm Seeding, *Tissue Donors, Brain Neoplasms / pathology / secondary, Carcinoma, Renal Cell / *pathology / secondary, Female, Heart Neoplasms / pathology / secondary, Heart Transplantation / *pathology, Heart Ventricles / pathology, Humans, Kidney Neoplasms / *pathology, Middle Aged, Postoperative Complications / pathology, Tomography, X-Ray Computed}, issn = {1053-2498 (Print) 1053-2498 (Linking)}, author = {Sack,F. U. and Lange,R. and Mehmanesh,H. and Amman,K. and Schnabel,P. and Zimmermann,R. and Dengler,T. and Otto,H. F. and Hagl,S.} }