@article {1192,
	title = {Hepatic transplantation for primary and metastatic cancers of the liver},
	journal = {Surgery},
	volume = {110},
	year = {1991},
	note = {0039-6060 (Print) Journal Article},
	month = {Oct},
	pages = {726 - 34; - discussion - 734-5},
	abstract = {Long-term results of transplantation for primary and metastatic hepatic malignancies were evaluated retrospectively in 637 patients. Recurrence rates and 2-year and 5-year patient survival rates were calculated. The overall recurrence rate was 40\%, with 81\% of deaths from recurrence occurring within 2 years after transplantation. Best results were obtained with uncommon tumors: incidental hepatomas (13\% recurrence; 57\% 2-year and 5-year follow-up); epithelioid hemangioendotheliomas (33\% recurrence; 82\% and 43\% 2-year and 5-year survival); hepatoblastomas (33\% recurrence; 50\% 2-year and 5-year survival); and fibrolamellar hepatomas (39\% recurrence; 60\% and 55\% 2-year and 5-year survival). Hemangiosarcomas had 64\% recurrence, and all patients died within 27.5 months. Tumors metastatic to the liver had 59\% recurrence, with 38\% and 21\% 2-year and 5-year survival rates. Transplantation should be abandoned for hemangiosarcomas and most metastatic tumors, except possibly for some slowly growing neuroendocrine tumors. The usual hepatomas had 39\% recurrence with 2-year and 5-year survival rates of 30\% and 18\%, respectively. Cholangiocarcinomas had 44\% recurrences with 2-year and 5-year survival rates of 30\% and 17\%, respectively. Transplantation for hepatomas and cholangiocarcinomas should be reserved for patients with favorable risk factors or when combined with well-defined chemotherapy protocols before and after operation.},
	keywords = {*Liver Transplantation, Adenoma, Bile Duct / secondary / *surgery, Adolescent, Adult, Aged, Carcinoma, Hepatocellular / secondary / *surgery, Child, Child, Preschool, Female, Hemangiosarcoma / secondary / *surgery, Humans, Infant, Liver Neoplasms / secondary / *surgery, Male, Middle Aged, Neoplasms, Unknown Primary, Research Support, U.S. Gov{\textquoteright}t, Non-P.H.S.},
	author = {Penn,I.}
}
